2026 Frontiers in Surgery

Traditional Chinese Medicine fumigation and Musk suppositories safely enhance postoperative recovery, reduce inflammation and complications, and elevate patient quality of life post-hemorrhoidectomy.

There are many types, patterns and causes of gastrointestinal symptoms. Common symptoms include stomach ulcers and acid reflux, bloating, hernias, diarrhoea and constipation as well as food intolerances.
Abdominal pain is one of the most frequent reasons for visiting a doctor or emergency department. Irritable bowel syndrome (IBS) causes abdominal pain, bloating and alternating constipation and diarrhoea. Crohn's disease and ulcerative colitis are inflammatory bowel diseases which cause symptoms such as diarrhoea and abdominal pain. Regular colonoscopy screening from the age of 50 years is the best way to detect and prevent bowel cancer.
Based on feedback collected from over 1,491 initial appointments for Stomach, Bowel & Digestive Symptoms, 83% of our surveyed patients reported improved quality of life after their first 4 appointments. See our detailed benchmarking statistics.
1,491
4
83%
91%
The age groups and genders we see most frequently with this condition. Note: this chart only represents the people who seek treatment at Ping Ming Health clinics for this condition.
| Age | Female % | Male % |
|---|---|---|
| 3 | 0 | 0.12 |
| 4 | 0 | 0.06 |
| 6 | 0.12 | 0.29 |
| 7 | 0.18 | 0.06 |
| 8 | 0.12 | 0.06 |
| 9 | 0.06 | 0.06 |
| 10 | 0.29 | 0.18 |
| 11 | 0.18 | 0.29 |
| 12 | 0.12 | 0.41 |
| 13 | 0.23 | 0.35 |
| 14 | 0.23 | 0.18 |
| 15 | 0.53 | 0.29 |
| 16 | 0.23 | 0.35 |
| 17 | 0.06 | 0 |
| 18 | 0.18 | 0.53 |
| 19 | 0.29 | 0.18 |
| 20 | 0.23 | 0.12 |
| 21 | 0.41 | 0.06 |
| 22 | 0.41 | 0.23 |
| 23 | 0.41 | 0.18 |
| 24 | 0.35 | 0.12 |
| 25 | 0.41 | 0.35 |
| 26 | 0.7 | 0.12 |
| 27 | 1.06 | 0.29 |
| 28 | 0.94 | 0.18 |
| 29 | 0.88 | 0.23 |
| 30 | 1.23 | 0.29 |
| 31 | 1.11 | 0.53 |
| 32 | 1.82 | 0.53 |
| 33 | 1.35 | 0.53 |
| 34 | 1.35 | 0.82 |
| 35 | 1.76 | 0.35 |
| 36 | 1.82 | 0.88 |
| 37 | 1.64 | 0.65 |
| 38 | 1.52 | 0.76 |
| 39 | 2.23 | 1.23 |
| 40 | 2.17 | 0.65 |
| 41 | 1.76 | 0.7 |
| 42 | 1.52 | 0.41 |
| 43 | 1.82 | 0.76 |
| 44 | 2.17 | 0.76 |
| 45 | 1.35 | 0.59 |
| 46 | 1.58 | 0.59 |
| 47 | 1.17 | 0.76 |
| 48 | 1.64 | 0.65 |
| 49 | 1.88 | 0.65 |
| 50 | 0.82 | 0.35 |
| 51 | 0.94 | 0.18 |
| 52 | 1.17 | 0.65 |
| 53 | 1.06 | 0.65 |
| 54 | 0.88 | 0.53 |
| 55 | 1.35 | 0.35 |
| 56 | 1.17 | 0.82 |
| 57 | 1.47 | 0.35 |
| 58 | 0.88 | 0.12 |
| 59 | 1.23 | 0.06 |
| 60 | 0.94 | 0.35 |
| 61 | 0.59 | 0.29 |
| 62 | 1.11 | 0.18 |
| 63 | 0.65 | 0.35 |
| 64 | 1.17 | 0.12 |
| 65 | 0.94 | 0.18 |
| 66 | 1.23 | 0.35 |
| 67 | 0.65 | 0.23 |
| 68 | 0.76 | 0.12 |
| 69 | 1.06 | 0.23 |
| 70 | 1.35 | 0.29 |
| 71 | 0.94 | 0.18 |
| 72 | 1 | 0.18 |
| 73 | 0.47 | 0.59 |
| 74 | 0.7 | 0.35 |
| 75 | 1.06 | 0.29 |
| 76 | 0.35 | 0.06 |
| 77 | 0.35 | 0.12 |
| 78 | 0.7 | 0.29 |
| 79 | 0.41 | 0.12 |
| 80 | 0.23 | 0.23 |
| 81 | 0.12 | 0.12 |
| 82 | 0.12 | 0.06 |
| 83 | 0.23 | 0.06 |
| 84 | 0.18 | 0.06 |
| 85 | 0.35 | 0.06 |
| 86 | 0.06 | 0 |
| 87 | 0.12 | 0.06 |
| 88 | 0.29 | 0.12 |
| 89 | 0.29 | 0.06 |
| 90 | 0.18 | 0 |
| 91 | 0.06 | 0 |
| 92 | 0 | 0.12 |
| 93 | 0.12 | 0.12 |
| 94 | 0.06 | 0.06 |
| 95 | 0.06 | 0 |
The average number of appointments that patients attend for this condition. Some conditions respond quickly while others may require ongoing treatment.
The types of treatments that are most frequently provided for this condition. Some treatments may be used in combination at the same time.
The following insights are obtained from systematic reviews and analysis of clinical trials investigating the efficacy of Chinese medicine and acupuncture for digestive health & bowel diseases.
2026 Frontiers in Surgery

Traditional Chinese Medicine fumigation and Musk suppositories safely enhance postoperative recovery, reduce inflammation and complications, and elevate patient quality of life post-hemorrhoidectomy.
2026 Journal of Pain Research

Wrist-ankle acupuncture (WAA) applied within 1 hour postoperatively significantly reduces pain, urinary retention and need for additional analgesics after a haemorrhoidectomy.
2026 Medicine

Acupuncture combined with Chinese herbal medicine is more efficacious in treating gastric ulcers than just Chinese herbal medicine alone.
2025 Journal of Pain Research

Wrist-ankle acupuncture in conjunction with patient-controlled intravenous analgesia significantly reduces postoperative pain and complications in patients undergoing Milligan-Morgan hemorrhoidectomy.
2025 Medicine

Chinese patent medicines, namely WWSC, PWC, WFCT, and KFXS, combined with Western medicines, show improved effectiveness in treating Helicobacter pylori-related gastric ulcers.
2024 Journal of Pain Research

The use of Snap Needles significantly enhances outcomes in the management of postoperative hemorrhoidal pain, potentially offering an alternative to western drug therapy.
2024 BMJ Open

Combination therapies with Chinese patent medicines, particularly Jianweiyuyang and Kangfuxin, show promise for treating peptic ulcers.
2024 AMB Express

Anweiyang capsule and Pinellia Heart-Draining Decoction improves Helicobacter pylori eradication, ulcer healing rate, and traditional Chinese Medicine syndromes in peptic ulcer patients, with a lower risk of adverse reactions.
2024 International Journal of Biological Macromolecules

A polysaccharide from Tremella aurantialba improves ulcerative colitis symptoms by targeting epithelial cell ferroptosis and modulating the gut microbiota.
2024 SSRN Electronic Journal

Diverse acupuncture therapies, especially moxibustion, emerged as superior methods for alleviating ulcerative colitis symptoms in clinical practice.
2024 Psychoneuroendocrinology

Peptic ulcers may be prevented and cured by well-chewed food rich in vegetable fibers and fermented milk products, which increase protective salivary mucus and decrease damaging bile flow.
2024 Heliyon

Acupuncture and moxibustion therapies have shown effectiveness in treating ulcerative colitis according to the summarised-findings of various systematic reviews and meta-analyses.
2023 International Journal of Colorectal Disease

Diltiazem ointment stands out as the most efficient medication in relieving pain post-open hemorrhoidectomy within a week of surgery.
2023 International Journal of Colorectal Disease

Electroacupuncture at the Baliao point treatment reduces short-term anal pain, swelling after hemorrhoid procedures, urinary retention incidents, and lessens postoperative analgesic drug use.
2023 Journal of PeriAnesthesia Nursing

Moxibustion significantly improved outcomes including symptom relief and time to first urination, over usual care, for patients experiencing postoperative urinary retention after anorectal surgeries.
2023 Healthcare

Electro-acupuncture could positively impact a range of medical conditions by modulating brain activity and connectivity related to pain, emotion, and cognition.
2023 Journal of Clinical Medicine

Rheumatoid arthritis-specific inflammation can be linked directly to the intestinal microbiota, thus, nutritional interventions against gut dysbiosis could function as a causal therapeutic approach.
2023 Autoimmunity Reviews

Intermittent fasting may potentially influence autoimmune diseases like type 1 diabetes and rheumatoid arthritis, by reducing inflammation and supporting cellular repair mechanisms.
2023 Chinese Herbal Medicines

Chinese herbal medicines could potentially relieve ulcerative colitis by moderating the gut microbiota and intestinal immunity loop.
2023 Frontiers in Pharmacology

Traditional Chinese medicine has been found to effectively treat ulcerative colitis by repairing various components of the damaged intestinal mucosal barrier.
2023 Medicine

Acupoint application has been proven to be a safe and effective method for the treatment of ulcerative colitis.
2023 Complementary Therapies in Medicine

Acupuncture demonstrates a positive therapeutic effect on inflammatory bowel disease (IBD) by effectively regulating associated inflammatory factors.
2023 Journal of Pharmacopuncture

Acupuncture combined with moxibustion has shown significant benefits in the treatment of mild to moderate Crohn's disease.
2023 Complementary Therapies in Medicine

Changes in gut microbiome associated with a low-fat, vegan diet and cooked soybeans may reduce the frequency and severity of postmenopausal hot flashes.
2022 Medicine

Electroacupuncture is effective in reducing postoperative pain in patients who have undergone surgery for mixed hemorrhoids.
2022 Phytomedicine

Combining conventional triple therapy with the Chinese herb formula Xiangsha Liujunzi significantly improves the treatment of Helicobacter pylori-positive peptic ulcer disease.
2022 Frontiers in Surgery

Acupuncture, particularly electro-acupuncture, may alleviate post-hemorrhoidectomy pain at certain stages, but overall effectiveness remains inconclusive.
2022 Frontiers in Pharmacology

The Chaihu Shugan Formula, a traditional Chinese medicine, not only effectively modulates intestinal gut microbiota but also strengthens gut barrier integrity and contains powerful anti-inflammatory properties.
2022 Frontiers in Pharmacology

Probiotics combined with traditional Chinese medicine have shown higher rates of efficiency in the treatment of ulcerative colitis than when each is used individually.
2022 Pharmacological Research - Modern Chinese Medicine

Patients with ulcerative colitis (UC) experienced greater clinical improvement and fewer adverse effects when treated with a combination of Traditional Chinese and Western medicine compared to Western medicine alone.
2022 Journal of Ethnopharmacology

Shenling Baizhu San (SBS), combined with mesalamine, can treat ulcerative colitis effectively by changing gut microbiota structures and increasing tryptophan metabolite levels.
2022 Phytomedicine

Chinese Herbal Medicine Prescriptions (CHMPs) have demonstrated to be potentially effective in managing Inflammatory Bowel Disease (IBD) with a comprehensive, holistic approach.
2022 Chinese Medicine

Chinese herbal medicine interventions, particularly those based on the Bai-Tou-Weng-Tang and Shen-Ling-Bai-Zhu-San formulas, show promise in treating Ulcerative Colitis.
2022 Evidence-Based Complementary and Alternative Medicine

Acupuncture can regulate both innate and adaptive immunity of IBD patients, including the balance of Th17/Treg and Th1/Th2 cells, and also modulate intestinal flora.
2022 EClinicalMedicine

Acupuncture effectively induced and sustained remission in active Crohn's disease patients, linked to an increase in anti-inflammatory gut bacteria and improved intestinal barrier.
2022 Journal of Acupuncture and Tuina Science

The combination of Tuina (Chinese therapeutic massage) and Shen Ling Bai Zhu San is more effective in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
2022 Computational and Mathematical Methods in Medicine

Acupuncture combined with moxibustion showed the best outcomes in terms of efficacy and quality of life improvement for adults with irritable bowel syndrome complicated with diarrhea.
2022 Frontiers in Medicine

Traditional Chinese medicine therapies, like acupuncture and moxibustion, effectively alleviate irritable bowel syndrome with diarrhea symptoms, and reduce recurrence rates.
2022 Frontiers in Neuroscience

Chinese herbal medicine shows promising and safe outcomes in relieving functional dyspepsia symptoms and associated psychological disorders.
2022 Frontiers in Pharmacology

Xiao Yao San can improve symptoms and reduce recurrence rates in patients with disorders of gut-brain interaction.
2022 The American Journal of Chinese Medicine

Acupuncture shows promising results in managing autoimmune diseases by potentially regulating immune responses.
2022 Applied Sciences

Fermented gold kiwi extract exhibits antioxidant properties, providing protection to the stomach lining and reducing inflammation, making it promising for treating gastritis and gastric ulcers.
2022 Frontiers in Nutrition

Meta-analysis indicates that fruit consumption, particularly kiwifruits, effectively alleviates constipation symptoms, offering valuable insights into improving gut health.
2022 Medicine

Acupuncture covering the depth ranges for BL18, BL20, and BL22 and their targeting of various tissues potentially alleviates sympathetic nerve issues and ischemia with assistance of the diaphragm.
2021 American Journal of Translational Research

Using a combined treatment of modified Buzhong Yiqi decoction and Gangtai ointment improves wound healing and anal function for circumferential mixed hemorrhoid patients.
2021 Biomedicine & Pharmacotherapy

Qing-Chang-Hua-Shi (QCHS) granules, a Chinese herbal formula, have shown significant efficacy in improving clinical remission and mucosal healing in moderately active ulcerative colitis patients.
2021 Anesthesiology and Pain Medicine

Acupuncture has shown promise as a complementary approach in treating chronic abdominal pain, providing symptom relief and improving quality of life.
2021 BMC Complementary Medicine and Therapies

Traditional Chinese Medicine may potentially be a viable treatment option for ulcerative colitis, but its effectiveness varies depending on the method of administration applied.
2021 Phytomedicine

Chinese medicine's unique immune regulation, intestinal flora regulation, and improved intestinal barrier function offer new approaches to managing chronic Inflammatory Bowel Disease.
2021 Phytomedicine

Chinese medicine presents unique advantages in managing Inflammatory Bowel Disease (IBD) through immune regulation, intestinal flora regulation, and improvement of intestinal barrier function.
2021 Pharmacological Research

Baicalin, a Scutellaria baicalensis extract, has been found to have numerous therapeutic applications in liver and gut diseases by mediating apoptosis and immune response pathways.
2021 Anesthesiology and Pain Medicine

Acupuncture is shown to be a beneficial supplementary treatment for chronic abdominal pain, improving patients' quality of life and cutting healthcare costs.
2021 Annals of Palliative Medicine

Traditional Chinese Medicine shows promise in preventing cholelithiasis recurrence post lithotripsy
2021 Frontiers in Public Health

Traditional Chinese medicine infant massage can reduce the symptoms of constipation in children suffering from functional constipation.
2021 Chinese Medicine

A variety of Chinese herbal medicines have been reported to effectively prevent or treat nonalcoholic fatty liver disease by regulation of the gut microbiota and the gut-liver axis.
2020 European Journal of Integrative Medicine

Auricular acupressure combined with acupuncture showed the highest effectiveness in reducing post-hemorrhoidectomy pain.
2020 Frontiers in Pharmacology

Kushen-based traditional Chinese medicine formulations show considerable potential and effectiveness in treating ulcerative colitis with meaningful improvement in clinical remission rate.
2020 European Journal of Integrative Medicine

Oral treatment with Six Gentlemen Decoction with Aucklandia and Amomum (SGDAA), a traditional Chinese medicine, significantly improves the treatment of Ulcerative colitis compared to conventional Western medicine.
2020 Nutrients

Unpasteurised milk and dairy products intake could potentially alter gut microbiome composition which may influence psychological functioning.
2020 Scientific Reports

Mu Dan Pi (MDP) and its water extract may serve as potential treatment options for inflammatory bowel disease.
2020 Biomedicine & Pharmacotherapy

Goji berry polysaccharide can enhance intestinal microbiota and beneficial bacteria levels, whilst modulating the innate immune response.
2020 Clinical and Translational Gastroenterology

Jia Wei Xiao Yao Wan showed an improvement in gastrointestinal symptoms for patients with functional dyspepsia who resisted conventional treatments.
2020 Frontiers in Pharmacology

Chinese medicine herb Bai Zhu might combat chronic gastritis by influencing inflammatory response, amino acid synthesis and energy metabolism.
2020 PLOS One

Ban Xia Xie Xin decoction has shown superior effectiveness and safety for treating chronic atrophic gastritis than patent medicine plus western medicine.
2020 Evidence-Based Complementary and Alternative Medicine

Acupuncture shows promise in treating postcholecystectomy syndrome.
2020 World Journal of Gastroenterology

Positive effects of acupuncture and electroacupuncture were observed in regulating gastric motility, gastric accommodation, mental status, gastrointestinal hormones, and central and autonomic functions while improving dyspeptic symptoms and quality of life.
2020 Evidence-Based Complementary and Alternative Medicine

Current evidence suggests that acupuncture is an efficient and safe treatment for functional constipation.
2020 Neural Plasticity

Acupuncture treatment can improve the clinical effectiveness of diarrhea-predominant irritable bowel syndrome or functional diarrhea.
2020 Evidence-Based Complementary and Alternative Medicine

Acupuncture at ST25 appears to be more effective than lactulose in the treatment of functional constipation.
2019 Acupuncture & Electro-Therapeutics Research

Acupuncture in conjunction with Chinese medicine has shown a higher efficiency compared to only Chinese medicine in haemorrhoids treatment.
2019 Nutrients

The diet might influence the onset and pathophysiology of ulcerative colitis, and can potentially be used in its management.
2019 Evidence-Based Complementary and Alternative Medicine

Traditional Chinese Medicine (TCM), when used alongside Western Medicine (WM), seems to improve treatment outcomes for Crohn's disease.
2019 Pain Research and Management

Acupuncture could be used as an adjunct in clinical settings to improve efficacy of western medicine for irritable bowel syndrome.
2018 Evidence-Based Complementary and Alternative Medicine

The herbal formula Modified Bu Zhong Yi Qi Tang significantly improves functional constipation symptoms with fewer adverse events.
2018 Evidence-Based Complementary and Alternative Medicine

Drinking alkaline-reduced water can improve the quality of life in patients suffering from diarrhea-predominant irritable bowel syndrome.
2018 Evidence-Based Complementary and Alternative Medicine

Acupuncture may improve diarrhoea-predominant irritable bowel syndrome better than drugs and has the fewest side effects.
2018 Inflammatory Bowel Diseases

Acupuncture has been shown to decrease disease activity and inflammation via increase of vagal activity in inflammatory bowel disease.
2017 Parasitology Research

The study indicates a positive link between Irritable Bowel Syndrome (IBS) and Blastocystis infection, with no such association found for Dientamoeba fragilis infection.
2017 PLOS One

Chinese herbal medicines showed greater improvement in terms of clinical efficacy in the treatment of irritable bowel syndrome with constipation than cisapride and mosapride.
2017 Trends in Food Science & Technology

The claimed health benefits of coix include anti-oxidation, anti-cancer, anti-inflammation, anti-allergy, enhancing immunological activity, regulating endocrine functions, anti-obesity, anti-diabetes, gastroprotection, hypolipidemia, and modulating gut microbiota.
2017 Acupuncture in Medicine

Patients receiving acupuncture combined with western medicine had a superior global symptom improvement compared with those receiving western medicine alone for gastro-oesophageal reflux disease.
2016 Journal of Food and Drug Analysis

Strictinin, the major phenolic compound in Pu'er teas, shows potential as a natural antibiotic and laxative but has greater inhibitory concentrations than some commercial antibiotics.
2016 Evidence-Based Complementary and Alternative Medicine

Acupuncture was superior to either sham acupuncture or medication (including Itopride, Mosapride, and Domperidone) in relieving the major symptoms of functional dyspepsia.
2015 World Journal of Gastroenterology

Acupuncture has the potential to treat gastrointestinal (GI) disorders by regulating GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis.
2013 Evidence-Based Complementary and Alternative Medicine

Acupuncture and moxibustion therapy show greater effectiveness than oral sulphasalazine in treating inflammatory bowel diseases.
2013 Evidence-Based Complementary and Alternative Medicine

Radish seed has been demonstrated to have beneficial effects on hypertension, obesity, diabetes mellitus, constipation, and cough.
2012 Scientific Reports

The traditional Chinese medicine diagnosis of Cold and Hot Syndromes based on tongue-coating appearance successfully detects signals in the tongue-coating microbiomes that are indicators of the entire body's status.
2010 Cochrane Database of Systematic Reviews

Traditional Chinese medicinal herbs may alleviate some symptoms of haemorrhoids, including bleeding and inflammation.
Although well-conducted clinical research can help members of the public to make better-informed decisions about their healthcare, we cannot claim that any particular treatment may be effective for any individual person.
When you consult with our Chinese medicine practitioners, you’ll receive personalised advice and treatment based on your symptoms and Chinese medicine diagnosis.
Browse our collection of scientific clinical research on acupuncture for digestive health & bowel diseases.
It includes recent and reputable papers published by peer-reviewed journals within the last 10 years.

2026, May 20
Traditional Chinese medicine fumigation combined with Musk hemorrhoid suppository for wound healing and inflammation control in patients with mixed hemorrhoids after Milligan-Morgan hemorrhoidectomy
Frontiers in Surgery
Zhao H, Liu Y, Zhao L, Na B Full Article

2026, Aug
Effects of Preemptive Analgesia Using Wrist-Ankle Acupuncture on Postoperative Pain and Urinary Retention After Haemorrhoidectomy: A Randomised, Three-Arm, Clinical Trial
Journal of Pain Research American Society of Pain & Neuroscience
He P, Kong J, Peng L, Li Y, Wu D, Ze L Full Article

2026, Mar 13
The efficacy of acupuncture combined with Chinese herbal medicine in the treatment of gastric ulcer: A systematic review and meta-analysis
Medicine
Liang YF, Qu WW, Zhu MD, Liu GF, Zheng X, Jiang Q, Han YL, Wang Q Full Article

2025, Sept
Wrist-Ankle Acupuncture Relieves Postoperative Pain After Milligan-Morgan Hemorrhoidectomy for Mixed Hemorrhoids: A Randomized Controlled Clinical Trial
Journal of Pain Research American Society of Pain & Neuroscience
Xu M, Li W, Wang X, Gao Y, Qi L, Xu L, He Y, Dong C, Zhang J, Zhang H, Wang J Full Article

2025, Feb 07
A comparison of the efficacy and safety of Chinese patent medicine combined with Western medicine for Helicobacter pylori-related gastric ulcer: A systematic review and network meta-analysis
Medicine
Zhong M, Sun Q, Ren B, Yu C, Zhou S, Gao Q, Wang X, Yuan C, Lu J, Peng Q, Zeng M, Song H Full Article

2024, Jun
Efficacy and Safety of Snap Needles in the Treatment of Postoperative Hemorrhoidal Pain: A Systematic Review and Meta-Analysis
Journal of Pain Research American Society of Pain & Neuroscience
Huang Q, Wang Y, Wang X, Xiang Z, Wang H, Wang A, Liu W, Gu Y Full Article

2024, Apr
Efficacy and safety of seven Chinese patent medicines combined with conventional triple/quadruple therapy forHelicobacter pylori-positive peptic ulcers: a systematic review and network meta-analysis
BMJ Open
Jiang Z, Deng B, Zhang Y, Li Y, Yu Z, Deng H, Chen Y Full Article

2024, Nov 08
Clinical effects of anweiyang capsule and Pinellia decoction for eradication of Helicobacter pylori and healing of peptic ulcers
AMB Express
Feng X, Zhao X, Cao L, Shang R, Feng X Full Article

2024, Nov
Tremella aurantialba polysaccharides alleviate ulcerative colitis in mice by improving intestinal barrier via modulating gut microbiota and inhibiting ferroptosis
International Journal of Biological Macromolecules
TA 2-1 polysaccharide demonstrated inhibition of ferroptosis in vitro and ameliorated symptoms in DSS-induced UC mice by repairing the intestinal barrier through upregulation of specific proteins, suggesting its protective effects are mediated by inhibiting ferroptosis and modulating the gut microbiota.
Peng G, Wang S, Zhang H, Xie F, Jiao L, Yuan Y, Ma C, Wu H, Meng Z Full Article

2024, Jan
Efficacy and Safety of Different Acupuncture Therapies for Patients with Ulcerative Colitis:A Systematic Review And Network Meta-Analysis
SSRN Electronic Journal
Various acupuncture therapies, including acupuncture, moxibustion, Acupoint catgut embedding, and combinations with Western medicine, demonstrate safety and effectiveness in treating UC. Moxibustion, especially when used alone or in combination with Western medicine, consistently ranks among the top interventions for improving overall effectiveness, reducing adverse reactions, and lowering recurrence rates of UC symptoms.
Zhang X, Yang S, Jin Y, Cheng X, Lu H, Wu H, Ji J Full Article

2024, Jan
New approaches to the pathogenesis of peptic ulcer based on the protective action of saliva with special reference to roughage, vegetable fibre and fermented milk products
Psychoneuroendocrinology
Bile, rather than hydrochloric acid, is suggested to play a causative role in the development of peptic ulceration, with saliva playing a protective role through the presence of mucus. Consumption of roughage, cellulose, vegetable fibers, and fermented milk products could aid in preventing and curing peptic ulcers by increasing salivary mucus production.
Malhotra SL Full Article

2024, Mar
Effects of acupuncture and moxibustion on ulcerative colitis: An overview of systematic reviews
Heliyon
Existing systematic reviews and meta-analyses on acupuncture and moxibustion for UC treatment exhibit significant methodological and outcome quality limitations. The overall evidence base is compromised by these shortcomings, suggesting caution in interpreting their findings for clinical practice. Future studies should adhere strictly to evidence-based guidelines for trial registration, design, and implementation to produce high-quality evidence in this area.
Wang D, Wang Q, Wang Y, Li T, Tian M Full Article

2023, Jan 07
Comparing the efficacy and safety of different analgesic strategies after open hemorrhoidectomy: a systematic review and network meta-analysis
International Journal of Colorectal Disease
Yang Y, Feng K, Lei Y, Qiu L, Liu C, Li G Full Article

2023, Apr 19
Electroacupuncture at Baliao point alleviates post-operative pain and anal distension after procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy): a prospective randomized clinical trial
International Journal of Colorectal Disease
Shen J, Zhou X, Zhao J, Wang H, Ye T, Chen W, Wang X, Gong L, Cai Y Full Article

2023, Dec
Moxibustion for Managing Postoperative Urinary Retention After Hemorrhoidectomy and Anorectal Surgeries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Journal of PeriAnesthesia Nursing
Liu CF, Chien LW Full Article

2023, Dec 19
Electro-Acupuncture Effects Measured by Functional Magnetic Resonance Imaging—A Systematic Review of Randomized Clinical Trials
Healthcare
Electro-acupuncture was found to modulate brain activity and connectivity in regions associated with pain perception, emotional regulation, and cognitive processing in conditions such as carpal tunnel syndrome, fibromyalgia, Crohn's disease, irritable bowel syndrome, and obesity.
Rodrigues JM, Ventura C, Abreu M, Santos C, Monte J, Machado JP, Santos RV Full Article

2023, Jun 28
Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis
Journal of Clinical Medicine
Disease activity scores improved in 19 of 20 RA patients after the intervention, with some achieving remission, along with decreased levels of inflammatory markers, suggesting a potential link between the gut microbiota and RA-specific inflammation.
Häupl T, Sörensen T, Smiljanovic B, Darcy M, Scheder-Bieschin J, Steckhan N, Hartmann AM, Koppold DA, Stuhlmüller B, Skriner K, Walewska BM, Hoppe B, Bonin M, Burmester GR, Schendel P, Feist E, Liere K, Meixner M, Kessler C, Grützkau A, Michalsen A Full Article

2023, Oct
Intermittent fasting: A promising dietary intervention for autoimmune diseases
Autoimmunity Reviews
Intermittent fasting may have beneficial effects on various autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus, by reducing inflammatory markers, modulating the immune system, altering and improving gut microbiota, and enhancing cellular repair mechanisms through autophagy. Evidence regarding other autoimmune diseases is limited and inconclusive, necessitating further research.
Barati M, Ghahremani A, Namdar Ahmadabad H Full Article

2023, Apr
Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis
Chinese Herbal Medicines
Chinese herbal medicines have shown a protective effect against ulcerative colitis by modulating gut microbiome and intestinal immunity, as supported by existing clinical trials.
Yang Y, Wang Y, Zhao L, Wang F, Li M, Wang Q, Luo H, Zhao Q, Zeng J, Zhao Y, Du F, Chen Y, Shen J, Wei S, Xiao Z, Wu X Full Article

2023, Oct 24
Repairing the intestinal mucosal barrier of traditional Chinese medicine for ulcerative colitis: a review
Frontiers in Pharmacology
Traditional Chinese Medicine (TCM) effectively treats ulcerative colitis (UC) by protecting and repairing various components of the intestinal mucosal barrier, involving mechanisms like increasing intestinal epithelial cells, tight junction proteins, and mucins, promoting stem cell proliferation, restoring intestinal microbiota, and modulating gut immunity.
Zong Y, Meng J, Mao T, Han Q, Zhang P, Shi L Full Article

2023, Aug 18
Efficacy and safety of acupoint application in the treatment of ulcerative colitis: A systematic review and meta-analysis
Medicine
Acupoint application demonstrates effectiveness in improving clinical comprehensive and syndrome effective rates, as well as interleukin-4 levels, while reducing interferon-γ levels in UC treatment compared to conventional western medicine. Colonoscopy and pathological examination outcomes and adverse reaction rates were comparable between acupoint application and conventional treatment. The evidence quality varies, with moderate quality for clinical comprehensive and syndrome outcomes, and lower quality for other indicators.
Tong Y, Yu Y, Yin S, Lin S, Chen Y, Su X Full Article

2023, Jun
Assessment of anti-inflammatory efficacy of acupuncture in patients with inflammatory bowel disease: A systematic review and meta-analysis
Complementary Therapies in Medicine
Acupuncture demonstrates positive therapeutic effects in IBD by regulating inflammatory factors, specifically TNF-α, IL-8, and IL-10, but not IL-1.
Yang X, He M, Tang Q, Wang Z, Jin D, Wu X, Yang Y, Ma D, Sun M, Li T Full Article

2023, Sept 30
The Effects of Acupuncture on Crohn’s Disease: a systematic review and meta-analysis
Journal of Pharmacopuncture
Acupuncture with moxibustion demonstrated significant effects compared to sham acupuncture with sham moxibustion in mild to moderate Crohn’s disease, as evidenced by improvements in effective rate and Crohn’s Disease Activity Index (CDAI) scores. However, the effect of acupuncture alone remains inconclusive, necessitating further studies with larger sample sizes and diverse patient groups.
Bae JH, Kang SY, You SE, Jeong HI, Jang S, Kim KH Full Article

2023, Dec
A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis
Complementary Therapies in Medicine
The study concluded that there were potential associations between changes in vasomotor symptoms and changes in the gut microbiome in response to a diet change.
Kahleova H, Holtz DN, Strom N, La Reau A, Kolipaka S, Schmidt N, Hata E, Znayenko-Miller T, Holubkov R, Barnard ND Full Article

2022, Dec 16
Electroacupuncture for postoperative pain in mixed hemorrhoids: A meta-analysis
Medicine
Du B, Xu Z, Zhong X Full Article

2022, Oct
Evidence construction of Chinese herbal formulae for the treatment of H. pylori positive peptic ulcer: A Bayesian network Meta-analysis
Phytomedicine
Yang J, Yang H, Dai Y, Jiang Y, Long Y, Zeng J, Ma X Full Article

2022, Mar 28
The Role of Acupuncture in Relieving Post-Hemorrhoidectomy Pain: A Systematic Review of Randomized Controlled Trials
Frontiers in Surgery
Although benefit of acupuncture on post-hemorrhoidectomy pain (PHP), especially electro-acupuncture (EA) on defecation after surgery, was observed at some time points, evidence on effectiveness of acupuncture on PHP was not conclusive.
Chen H, Zhang W, Sun Y, Jiao R, Liu Z Full Article

2022, Mar 15
The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue™ Cell Co-Culture Model
Frontiers in Pharmacology
CSF stimulated the production of beneficial short-chain fatty acids (SCFA), promoted the growth of health-related Bifidobacterium species, reduced the abundance of opportunistic pathogenic Escherichia coli, improved intestinal barrier integrity, and exhibited anti-inflammatory properties by modulating cytokine production.
Liu L, Lu Y, Xu C, Chen H, Wang X, Wang Y, Cai B, Li B, Verstrepen L, Ghyselinck J, Marzorati M, Yao Q Full Article

2022, Mar 07
Efficacy and Safety of Probiotics Combined With Traditional Chinese Medicine for Ulcerative Colitis: A Systematic Review and Meta-Analysis
Frontiers in Pharmacology
The combination of probiotics with TCM demonstrates superior efficacy compared to 5-aminosalicylic acid (5-ASA), probiotics alone, or TCM alone in managing UC. This approach effectively controls clinical symptoms, reduces intestinal inflammation, and lowers recurrence rates with minimal adverse events. Utilizing a mixture of different probiotics alongside individually tailored TCM appears to be a promising clinical strategy for UC treatment.
Hu Y, Ye Z, She Y, Li L, Wu M, Qin K, Li Y, He H, Hu Z, Yang M, Lu F, Ye Q Full Article

2022, Sept
Efficacy of integrated traditional Chinese and Western medicine on ulcerative colitis: A systematic review and meta-analysis
Pharmacological Research - Modern Chinese Medicine
Integrated Traditional Chinese Medicine and Western Medicine (ITCMWM) therapy demonstrates superior clinical effectiveness compared to Western medicine (WM) alone for treating UC, with similar safety profiles. Further research is needed to assess the long-term therapeutic effects of ITCMWM in UC treatment.
Chen S, Ji G, Liu X, Yang M, Zhang Y, Cao J, Pan Y Full Article

2022, Jun
Shenling Baizhu San ameliorates ulcerative colitis by regulating the gut microbiota and its tryptophan metabolites: A complementary medicine to mesalamine
Journal of Ethnopharmacology
Shenling Baizhu San (SBS) combined with mesalamine effectively improves clinical and endoscopic outcomes in ulcerative colitis (UC) patients by altering gut microbiota structures and increasing microbial tryptophan metabolites.
Jiao C, Zhang Q, Yang M, Ma J, Zhao X, Tang N, Dai M, Li Q, Jiang Z, Huang X, Zhang H, Sun L Full Article

2022, Jul
Holism of Chinese herbal medicine prescriptions for inflammatory bowel disease: A review based on clinical evidence and experimental research
Phytomedicine
Chinese herbal medicine prescriptions (CHMPs) demonstrate significant potential in managing IBD through their complex and holistic mechanisms of action, which can be elucidated using high-throughput analysis, omics, gut microbiome studies, and network pharmacology.
Zhang S, Luo H, Tan D, Peng B, Zhong Z, Wang Y Full Article

2022, Apr 04
Chinese herbal medicines in the treatment of ulcerative colitis: a review
Chinese Medicine International Society for Chinese Medicine
Chinese herbal medicines (CHM), particularly CHM formulas guided by CM pattern identification, are commonly used in treating UC, with Large Intestine Dampness-Heat and Spleen Deficiency identified as predominant CM patterns. Bai-Tou-Weng-Tang and Shen-Ling-Bai-Zhu-San are frequently prescribed formulas, alongside commonly used single herbs such as Huang Lian and Bai Zhu. Safety assessments of CHM formulas remain limited, highlighting the need for further well-designed randomized controlled trials (RCTs) to validate these findings and ensure safety.
Zhang X, Zhang L, Chan JCP, Wang X, Zhao C, Xu Y, Xiong W, Chung WC, Liang F, Wang X, Miao J, Bian Z Full Article

2022, Jan 15
A Review on the Immunomodulatory Mechanism of Acupuncture in the Treatment of Inflammatory Bowel Disease
Evidence-Based Complementary and Alternative Medicine
Acupuncture has demonstrated effectiveness in treating IBD by modulating both innate and adaptive immune responses. It regulates innate immunity through effects on the intestinal epithelial barrier, toll-like receptors, NLRP3 inflammasomes, oxidative stress, and endoplasmic reticulum stress. Additionally, acupuncture influences adaptive immunity by balancing Th17/Treg and Th1/Th2 cells. Furthermore, acupuncture can impact intestinal flora, highlighting its comprehensive immunomodulatory effects in IBD treatment.
Liu Z, Jiao Y, Yu T, Wang H, Zhang Y, Liu D, Xu Y, Guan Q, Lu M Full Article

2022, Mar
Acupuncture improves the symptoms, intestinal microbiota, and inflammation of patients with mild to moderate Crohn's disease: A randomized controlled trial
EClinicalMedicine
Acupuncture was effective in inducing and maintaining remission in patients with active Crohn's disease, associated with increased anti-inflammatory intestinal bacteria, enhanced intestinal barrier, and regulation of Th1/Th17-related cytokines.
Bao C, Wu L, Wang D, Chen L, Jin X, Shi Y, Li G, Zhang J, Zeng X, Chen J, Liu H, Wu H Full Article

2022, Feb
Clinical study on Tuina plus Shen Ling Bai Zhu San in treating children with diarrhea due to spleen deficiency
Journal of Acupuncture and Tuina Science
Tuina plus Shen Ling Bai Zhu San has a better therapeutic effect in treating pediatric diarrhea due to spleen deficiency than Shen Ling Bai Zhu San alone.
Li J Full Article

2022, Jun 28
Acupuncture and Moxibustion in the Treatment of Adult Diarrhea Irritable Bowel Syndrome: A Network Meta-analysis
Computational and Mathematical Methods in Medicine
Acupuncture+sandwiched moxibustion has the best effect on improving the efficacy and quality of life (QOL) of irritable bowel syndrome complicated with diarrhea (IBS-D) patients.
Jiang X, Guo X, Zhou J, Ye S Full Article

2022, Aug 09
External therapy of traditional Chinese medicine for treating irritable bowel syndrome with diarrhea: A systematic review and meta-analysis
Frontiers in Medicine
External therapy of TCM for IBS-D alleviated abdominal symptoms, improved clinical effectiveness, and reduced recurrence with great safety. However, because of the limitations of publication bias in trials, more rigorous studies with a clinical design are necessary for further verification of the outcomes.
Wei X, Wen Y, Wei Y, Liang X, Ma X, Zhang B, Tang X Full Article

2022, Jul 14
Chinese Herbal Medicine for Functional Dyspepsia With Psychological Disorders: A Systematic Review and Meta-Analysis
Frontiers in Neuroscience
The current evidence shows that CHM treatment has great potential and safety in alleviating the symptoms of FD and improving the psychological disorders of anxiety and depression in patients with FD.
Luo X, Wang L, Fang S, Qing X, Jiang T, Yang Y, Su X, Wei W Full Article

2022, Jan 20
Efficacy and Safety of Chinese Herbal Medicine Xiao Yao San in Functional Gastrointestinal Disorders: A meta-Analysis and Trial Sequential Analysis of Randomized Controlled Trials
Frontiers in Pharmacology
Our study showed that Xiao-Yao-San (XYS) was effective in the treatment of functional gastrointestinal disorders (FGIDs), including functional dyspepsia (FD), irritable bowel syndrome (IBS) and functional constipation (FC), which could reduce the overall symptom score,Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores of patients and reduce the recurrence rate. Therefore, XYS may be a potential candidate for the treatment of FGIDs.
Liu Q, Shi Z, Zhang T, Jiang T, Luo X, Su X, Yang Y and Wei W Full Article

2022, Mar 10
Therapeutic Effect and Mechanism of Acupuncture in Autoimmune Diseases
The American Journal of Chinese Medicine
The study concludes that acupuncture has shown promising results in the treatment of autoimmune diseases such as multiple sclerosis (MS), rheumatoid arthritis (RA), and inflammatory bowel disease (IBD), although its mechanism is not fully understood.
Jing Wang, Fangyi Zhu, Wei Huang, Zhengyi Chen, Ping Zhao, Yanting Lei, Yumei Liu, Xijun Liu, Bo Sun, Hulun Li Full Article

2022, May 23
Gastroprotective Effects of Fermented Gold Kiwi (Actinidia chinenesis L.) Extracts on HCl/EtOH-Induced Gastric Injury in Rats
Applied Sciences
These results suggest that fermented gold kiwi (FGK) can decrease the inflammatory response and protect the gastric mucosa. FGK therefore has the potential to prevent and treat gastritis and gastric ulcers.
Jeon EJ, Choi JH, Lee NY, Oh HJ, Kwon HS, Kwon J Full Article

2022, Oct 06
Effect of fruit intake on functional constipation: A systematic review and meta-analysis of randomized and crossover studies
Frontiers in Nutrition
Fruit intake may have potential symptom alleviation on the FC as evidence shows that they can affect stool consistency, stool frequency, and gut microbiota. Further large-scale studies are needed to gain more confident conclusions concerning the association between fruit intake and FC in the future.
Huo J, Wu L, Lv J, Cao H, Gao Q Full Article

2022, Oct 28
Anatomical structures and needling method of the back-shu points BL18, BL20, and BL22 related to gastrointestinal organs: A PRISMA-compliant systematic review of acupoints and exploratory mechanism analysis
Medicine
This study provides guidance on applying needles in terms of anatomical structures to yield therapeutic responses. However, few studies have assessed how to effectively stimulate BSP to trigger digestive effects and their mechanisms. Additional studies on the relationship between BSP and the digestive system are needed to use these acupoints for digestive diseases.
Cho Y, Han Y, Kim Y, Han S, Oh K, Chae H, Hongmin C, Ryu M Full Article

2021, Jul 15
The effects of modified Buzhong Yiqi decoction combined with Gangtai ointment on the wound healing and anal function in circumferential mixed hemorrhoid patients
American Journal of Translational Research
Modified Buzhong Yiqi decoction combined with Gangtai ointment for patients with circumferential mixed hemorrhoids has good short-term efficacy. It helps to promote wound healing, improves anal function, and does not increase the incidence of adverse reactions. It is worthy of promotion and application.
Lu B, Du J, Wu X Full Article

2021, Jul
Randomised clinical trial: Efficacy and safety of Qing-Chang-Hua-Shi granules in a multicenter, randomized, and double-blind clinical trial of patients with moderately active ulcerative colitis
Biomedicine & Pharmacotherapy
QCHS granules were found to be superior to placebo in inducing clinical remission, mucosal healing, and relieving mucus/blood stool in patients with moderately active and 5-ASA-refractory UC.
Shen H, Zhang S, Zhao W, Ren S, Ke X, Gu Q, Tang Z, Xie J, Chen S, Chen Y, Zou J, Zhang L, Shen Z, Zheng K, Liu Y, Gu P, Cheng J, Hu J, Zhu L Full Article

2021, Mar 17
Efficacy of Acupuncture in the Treatment of Chronic Abdominal Pain
Anesthesiology and Pain Medicine
Acupuncture is a complementary approach that can help reduce symptoms and improve the quality of life for patients with chronic abdominal pain, specifically those with IBS and IBD syndromes.
Berger AA, Liu Y, Jin K, Kaneb A, Welschmeyer A, Cornett EM, Kaye AD, Imani F, Khademi SH, Varrassi G, Viswanath O, Urits I Full Article

2021, Sept 13
An evidence mapping of systematic reviews and meta-analysis on traditional Chinese medicine for ulcerative colitis
BMC Complementary Medicine and Therapies
The treatment of UC with TCM can only be recommended cautiously due to the very low quality of included systematic reviews and the variability in disease stages, disease classification, and intervention administration routes reported.
Sun YX, Wang X, Liao X, Guo J, Hou WB, Wang X, Liu JP, Liu ZL Full Article

2021, Nov
A recent update on the use of Chinese medicine in the treatment of inflammatory bowel disease
Phytomedicine
Chinese medicine shows promise in the management of IBD by addressing its pathogenesis through mechanisms such as immune modulation, regulation of intestinal flora, and enhancement of intestinal barrier function. This review underscores the potential of classical multi-herbal Chinese medicine as a therapeutic option for IBD, highlighting the need for further exploration and evaluation.
Yang L, Luo H, Tan D, Zhang S, Zhong Z, Wang S, Vong CT, Wang Y Full Article

2021, Mar
Baicalin and the liver-gut system: Pharmacological bases explaining its therapeutic effects
Pharmacological Research
Baicalin exerts protective effects on liver and gut diseases by mediating downstream apoptosis and immune response pathways induced by oxidative stress and inflammation.
Hu Q, Zhang W, Wu Z, Tian X, Xiang J, Li L, Li Z, Peng X, Wei S, Ma X, Zhao Y Full Article

2021, Dec
Systematic review and pathway enrichment analysis of Chinese medicine in preventing recurrence and improving prognosis of cholelithiasis after gallbladder-preserving lithotripsy
Annals of Palliative Medicine
Existing evidence suggests that the use of TCM may reduce the recurrence rate after gallbladder-preserving lithotripsy and this effect may be related to the flavonoid glycoside naringin from Glycyrrhiza uralensis, but more RCTs with high quality in this area may be needed to have a robust conclusion.
Li B, Lin Y, Nie B, Zhao G, Zhang X, Zhu M, Hu J, Huang P, Feng S, Qiu R, Tian G, Zhang S, Shang H Full Article

2021, Jun 11
Clinical Efficacy of Infantile Massage in the Treatment of Infant Functional Constipation: A Meta-Analysis
Frontiers in Public Health
TCM infant massage can increase defecation frequency and reduce the symptoms of constipation in children suffering from functional constipation; in addition, the clinical trial showed beneficial effects.
Zhi Liu, Li Gang, Ma Yunwei, Ling Lin Full Article

2021, Jul 27
Herbal therapy for ameliorating nonalcoholic fatty liver disease via rebuilding the intestinal microecology
Chinese Medicine International Society for Chinese Medicine
The key roles of CHMs in the regulation of gut microbiota and the gut-liver axis along with their mechanisms (such as modulating intestinal permeability, reducing the inflammatory response, protecting liver cells, improving lipid metabolism, and modulating nuclear receptors), were well summarized. All the knowledge and information presented here will be very helpful for researchers to better understand the applications and mechanisms of CHMs for treatment of NAFLD.
Yang XF, Lu M, You L, Gen H, Yuan L, Tian T, Li CY, Xu K, Hou J, Lei M Full Article

2020, Aug
Acupuncture and related techniques for postoperative pain after hemorrhoidectomy: A systematic review and network meta-analysis
European Journal of Integrative Medicine
Auricular acupressure plus acupuncture provided the best outcomes but findings were limited by the quality of the evidence.
Qin D, Zhang AM, Chen M, Tang TC, Du YJ, Zheng H Full Article

2020, Dec 10
Efficacy and Safety of Sophora flavescens (Kushen) Based Traditional Chinese Medicine in the Treatment of Ulcerative Colitis: Clinical Evidence and Potential Mechanisms
Frontiers in Pharmacology
Kushen-based TCM formulations demonstrate higher clinical remission rates and lower incidence of adverse events in the treatment of UC with DHAS, likely involving key components and the PI3K-Akt signaling pathway.
Chen M, Ding Y, Tong Z Full Article

2020, Jun
Six Gentlemen Decoction adding Aucklandia and Amomum (Xiangsha Liujunzi Tang) for the treatment of ulcerative colitis: A systematic review and meta-analysis of randomized clinical trials
European Journal of Integrative Medicine
SGDAA treatment for ulcerative colitis, especially when administered for more than 4 weeks, was found to be more effective in terms of treatment response and curative response compared to conventional Western medicine or other Chinese medicine. The meta-analysis included seven RCTs with 614 colitis patients, highlighting the potential superiority of oral SGDAA for the treatment of ulcerative colitis.
Yuan H, Zhang T, Huang S, Zhou J, Park S Full Article

2020, May 19
Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome
Nutrients
Unpasteurised dairy intake was associated with an increased abundance of the probiotic genus Lactobacillus, higher levels of faecal short-chain fatty acids, and improved gut microbiome diversity, potentially benefiting physical and mental health.
Butler MI, Bastiaanssen TFS, Long-Smith C, Berding K, Morkl S, Cusack AM, Strain C, Busca K, Porteous-Allen P, Claesson MJ, Stanton C, Cryan JF, Allen D, Dinan TG Full Article

2020, Oct 14
A systematic identification of anti-inflammatory active components derived from Mu Dan Pi and their applications in inflammatory bowel disease
Scientific Reports
MDP and its water extract, particularly 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG), demonstrated significant inhibition of NF-κB and IRF reporters, as well as IL-6 and TNF-α production, suggesting potential as a novel therapy for IBD.
Chen TF, Hsu JT, Wu KC, Hsiao CF, Lin JA, Cheng YH, Liu YH, Lee DY, Chang HH, Cho DY, Hsu JL Full Article

2020, Jan
Prebiotic, immuno-stimulating and gut microbiota-modulating effects of Lycium barbarum polysaccharide
Biomedicine & Pharmacotherapy
The study concludes that LBP supports the growth of selective probiotic bacteria, enhances the intestinal microbiota, boosts beneficial bacteria levels, and modulates the innate immune response.
Zhu W, Zhou S, Liu J, McLean RJC, Chu W Full Article

2020, Oct
An Herbal Formulation of Jiawei Xiaoyao for the Treatment of Functional Dyspepsia: A Multicenter, Randomized, Placebo-Controlled, Clinical Trial
Clinical and Translational Gastroenterology
The Jiawei Xiaoyao (JX) pill was superior to the placebo in terms of improving the Gastrointestinal Symptom Score (GIS) in patients with functional dyspepsia (FD) but did not significantly improve depression or anxiety symptoms.
Chen G, Feng P, Wang S, Ding X, Xiong J, Wu J, Wang L, Chen W, Chen G, Han M, Zou T, Li L, Du H Full Article

2020, Jan 29
Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis
Frontiers in Pharmacology
We showed that AMK probably influences the inflammatory response, amino acid synthesis, and energy metabolism when treating CG. This study provides novel insights for researchers to explore the mechanism of action of TCM systematically.
Yang S, Zhang J, Yan Y, Yang M, Li C, Li J, Zhong L, Gong Q, Yu H Full Article

2020, Oct 27
Efficacy of Banxia Xiexin decoction for chronic atrophic gastritis: A systematic review and meta-analysis
PLOS One Public Library of Science
The meta-analysis showed that Banxia Xiexin decoction (BXD) was more effective and safer for chronic atrophic gastritis (CAG) patients than the control group
Cao Y, Zheng Y, Niu J, Zhu C, Yang D, Rong F, et al. Full Article

2020, Jul 30
Acupuncture for the Postcholecystectomy Syndrome: A Systematic Review and Meta-Analysis
Evidence-Based Complementary and Alternative Medicine
The results of this review indicate that acupuncture may improve the overall symptoms of postcholecystectomy syndrome. The reported acupuncture-related adverse events are mild and acceptable. However, this study lacks conclusive evidence due to poor quality evidence, limited data, and clinical heterogeneity of acupuncture methods in the included studies.
Yin Z, Xiao Q, Xu G, Cheng Y, Yang H, Zhou J, Fu Y, Chen J, Zhao L, Liang F Full Article

2020, May 21
Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review
World Journal of Gastroenterology
Guo Y, Wei W, Chen JD Full Article

2020, Jul
The Effectiveness of Acupuncture in Management of Functional Constipation: A Systematic Review and Meta-Analysis
Evidence-Based Complementary and Alternative Medicine
This systematic review suggests that acupuncture for FC is safe and effective. It is reduced stool frequency and improved constipation symptoms and stool formation. It also showed that acupuncture may be more effective than pharmacological treatment. Therefore, it has less side effects and improving overall quality of life.
Wang, Lu; Xu, Mingmin; Zheng, Qianhua; Zhang, Wei; Li, Ying. Full Article

2020, Nov 23
Acupuncture for Adults with Diarrhea-Predominant Irritable Bowel Syndrome or Functional Diarrhea: A Systematic Review and Meta-Analysis
Neural Plasticity
Acupuncture treatment can improve the clinical effectiveness of IBS-D or FD, with great safety. It significantly reduces the pain levels, inflammations, and decreases the recurrence rate. It also reported that 60% of patients have stopped taking the medication due to improvements in symptoms. It has overall improved the quality of life for IBS patients.
Jianbo Guo, Xiaoxiao Xing, Jiani Wu, Hui Zhang, Yongen Yun, Zongshi Qin, and Qingyong He Full Article

2020, Nov 6
Efficacy and Safety of Acupuncture at Tianshu (ST25) for Functional Constipation: Evidence from 10 Randomized Controlled Trials
Evidence-Based Complementary and Alternative Medicine
The meta-analysis demonstrates that acupuncture relief frequency of bowel movements, decreased painful evacuation and abdominal pain for Functional Constipation (FC). It also showcase improvement in long-term effect of defecation as compared to short-term effects with patients.
Li P, Luo Y, Wang Q, Shu S, Chen K, Yu D, Fan C. Full Article

2019, Jun 01
A meta-analysis of the clinical efficacy of the combination of acupuncture and Chinese medicine in the treatment of haemorrhoids
Acupuncture & Electro-Therapeutics Research
The treatment of combination of acupuncture and Chinese medicine in haemorrhoids is more useful than Chinese medicine alone applied in piles, which is shown in 91% of clinical effects in average.
Zeng M, Cheng X, Chen G, Kou J Full Article

2019, Jun 30
Diet in the Pathogenesis and Management of Ulcerative Colitis; A Review of Randomized Controlled Dietary Interventions
Nutrients
The study concludes that although many patients associate symptoms or disease relapse with dietary factors, there is a lack of well-designed randomized controlled trials investigating the role of diet in managing ulcerative colitis.
Keshteli AH, Madsen KL, Dieleman LA Full Article

2019, Mar 05
Adjuvant Treatment of Crohn’s Disease with Traditional Chinese Medicine: A Meta-Analysis
Evidence-Based Complementary and Alternative Medicine
TCM combined with WM shows significant advantages over WM alone in inducing remission and managing symptoms of Crohn’s disease, including improvements in total effective rate, remission maintenance rate, reduction of inflammatory markers (CRP and ESR), clinical scores, and adverse events. However, the overall quality of the included RCTs was low, necessitating higher quality studies to confirm these findings.
Wang Y, Li M, Zha AS Full Article

2019, Nov 11
Comparison between the Effects of Acupuncture Relative to Other Controls on Irritable Bowel Syndrome: A Meta-Analysis
Pain Research and Management
This meta-analysis research collectively showed that acupuncture has a higher efficacy rate when combined with western medicine. Patients showed improved long term clinical symptoms such as abdominal pain and altered defecation habits, thus and overall greater quality of life.
Zheng H, Chen R, Zhao X, Li G, Liang Y, Zhang H, Chi Z Full Article

2018, Jan
Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials
Evidence-Based Complementary and Alternative Medicine
This review suggests that Modified Buzhong-Yiqi-Tang (MBYT) appears to have excellent therapeutic effect on adult patients with functional constipation and no serious side effects were identified.
Gong H, Qin F, He H Full Article

2018, Jan
Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study
Evidence-Based Complementary and Alternative Medicine
In a randomized controlled trial involving 27 patients with diarrhea-predominant IBS, those who ingested at least 2 liters/day of alkaline-reduced water (ARW) for eight weeks showed significant improvement in IBS quality-of-life scores compared to the control group ingesting placebo water. Additionally, a higher percentage of patients in the ARW group reported symptom improvement, and the abdominal pain score showed a numerical decrease in the ARW group. The findings suggest that the consumption of ARW for eight weeks may positively impact the quality of life in individuals with diarrhea-predominant IBS.
Shin DW, Yoon H, Kim HS, Choi YJ, Shin CM, Park YS, Kim N, Lee DH Full Article

2018, May 27
Acupuncture for Diarrhoea-Predominant Irritable Bowel Syndrome: A Network Meta-Analysis
Evidence-Based Complementary and Alternative Medicine
This meta analysis and systematic review article showed that acupuncture improve diarrhoea symptoms with IBS. Patients experienced less diarrhoea, abdominal hypersensitivity and side effects from Western medication (e.g. gastrointestinal disorder inflammatory drugs)
Zhu L, Ma Y, Ye S, Shu Z Full Article

2018, Dec 11
Acupuncture in Inflammatory Bowel Disease
Inflammatory Bowel Diseases Crohn's & Colitis Foundation
This review have showed effectiveness of acupuncture in IBD with history and methodology of acupuncture. Symptoms such as abdominal pain, impaired gastrointestinal tract , depression/anxiety, and hypersensitivity have significantly improved. Patients also reported a better overall quality of life of patients.
Gengqing Song, MD, Claudio Fiocchi, MD, Jean-Paul Achkar, MD Full Article

2017, Jul 01
The role of Blastocystis sp. and Dientamoeba fragilis in irritable bowel syndrome: a systematic review and meta-analysis
Parasitology Research
Individuals infected with Blastocystis were found to have a positive association with IBS, with a pooled odds ratio of 2.19, while no significant association was observed for Dientamoeba fragilis infection.
Rostami A, Riahi SM, Haghighi A, Saber V, Armon B, Seyyedtabaei SJ Full Article

2017, Dec 18
Systematic review and meta-analysis of traditional Chinese medicine in the treatment of constipation-predominant irritable bowel syndrome
PLOS One Public Library of Science
Traditional Chinese medicine (TCM) showed greater improvement in terms of clinical efficacy in the treatment of irritable bowel syndrome with constipation (IBS-C) than cisapride and mosapride.
Dan-yan Li , Yun-kai Dai , Yun-zhan Zhang, Meng-xin Huang, Ru-liu Li, Jia Ou-yang, Wei-jing Chen, Ling Hu Full Article

2017, Mar
Coix: Chemical composition and health effects
Trends in Food Science & Technology
The study indicated that pearl barley benefits include anti-oxidation, anti-cancer, anti-inflammation, anti-allergy, enhancing immunological activity, regulating endocrine functions, anti-obesity, anti-diabetes, gastroprotection, hypolipidemia, and modulating gut microbiota
Fan Zhu Full Article

2017, Oct
Acupuncture for the treatment of gastro-oesophageal reflux disease: a systematic review and meta-analysis
Acupuncture in Medicine British Medical Acupuncture Society
This journal study suggests that acupuncture improve recurrence rates compared with Western Medicine (WM) when used alone. Acupuncture lead to greater overall improvement when used as an adjunct to WM in patients with GORD. They may also have a positive impact on quality of life.
Zhu, J., Guo, Y., Liu, S., Su, X., Li, Y., Yang, Y., Hou, L., Wang, G., Zhang, J., Chen, J. J. D., Wang, Q., Wei, R., & Wei, W. Full Article

2016, Oct
Antibacterial and laxative activities of strictinin isolated from Pu'er tea ( Camellia sinensis )
Journal of Food and Drug Analysis
The study concludes that strictinin has antibacterial activities against Propionibacterium acnes and Staphylococcus epidermidis, and also exhibits laxative activity by accelerating small intestinal transit in rats.
Hsieh SK, Xu JR, Lin NH, Li YC, Chen GH, Kuo PC, Chen WY, Tzen JTC Full Article

2016, Dec 29
Acupuncture for Functional Dyspepsia: What Strength Does It Have? A Systematic Review and Meta-Analysis of Randomized Controlled Trial
Evidence-Based Complementary and Alternative Medicine
Based on current available evidence, acupuncture therapy achieves statistically significant effect for functional dyspepsia in comparison with sham acupuncture and is superior to medication (prokinetic agents) in improving the symptoms and quality of life of functional dyspepsia patients.
Bo Pang, Tao Jiang, Yuan-Hao Du, Jing Li, Bo Li, Ya-Cai Hu, Qiu-Han Ca Full Article

2015, Jul 21
Acupuncture and regulation of gastrointestinal function
World Journal of Gastroenterology
In this review, we discuss the regulation on gastrointestinal (GI) function through acupuncture from the perspectives of GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis. The results of studies in both humans and animals suggest that acupuncture has the potential to treat GI disorders by regulating GI motility, the GI barrier, visceral sensitivity, and the brain-gut axis. In addition, the dual regulatory effects and the intensity-dependent nature of acupuncture on GI motility are discussed.
Li H, He T, Xu Q, Li Z, Liu Y, Li F, Yang BF, Liu CZ. Full Article

2013, Sept 24
Acupuncture and Moxibustion for Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Evidence-Based Complementary and Alternative Medicine
This review suggests that acupuncture and moxibustion therapy demonstrates better efficacy than oral sulphasalazine (SASP) in treating inflammatory bowel diseases. However, robust evidence is limited and higher-quality randomised controlled trials are needed.
Ji, J., Lu, Y., Liu, H., Feng, H., Zhang, F., Wu, L., Cui, Y., & Wu, H. Full Article

2013, Jul 8
A Review of the Phytochemistry and Pharmacological Activities of Raphani Semen
Evidence-Based Complementary and Alternative Medicine
This systematic review showcased that Raphani Semen (Radish Seed) or more commonly known as LaiFuZi in Chinese Medicine, is found to have antihypertensive effects (hypertension), antilipase activities (treatment for obesity), gastrointestinal activities, constipation and antitussive effects. Thus, commonly used in Chinese Medicine for treatments.
Tung-Ting Sham, Ailsa Chui-Ying Yuen, Yam-Fung NgChi-On ChanDaniel Kam-Wah Mok, and Shun-Wan Chan Full Article

2012, Dec
Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome
Scientific Reports
The results reveal an important connection between the tongue-coating microbiome and traditional tongue diagnosis and illustrate the potential of the tongue-coating microbiome as a novel holistic biomarker for characterizing patient subtypes.
Bai Jiang, Xujun Liang, Yang Chen, Tao Ma, Liyang Liu, Junfeng Li, Rui Jiang, Ting Chen, Xuegong Zhang & Shao Li Full Article

2010, Oct 06
Traditional Chinese Medicine herbs for stopping bleeding from haemorrhoids
Cochrane Database of Systematic Reviews Cochrane
This review did not provide strong evidence concerning the effectiveness of TCMHs for stopping bleeding from haemorrhoids.
Gan T, Liu Y, Wang Y, Yang J Full Article

It is by virtue of the twelve channels that human life exists, that disease arises, that human beings can be treated and illness cured. The twelve channels are where beginners start and masters end.